Laboratory Services

Zinc, Serum

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Updated Test Information:

Test Description
Zinc, Serum
Synonym(s)

Zn (Zinc) Serum

Test ID
ZNS
General Information

Useful for detecting zinc deficiency

Specimen Type

Serum

Specimen Requirements

6-mL Plain, royal blue-top Vacutainer plastic trace element blood collection tube

Specimen Collection / Processing Instructions

  • Patient Preparation: High concentrations of gadolinium, iodine, and barium are known to interfere with most metals tests. If gadolinium-, iodine-, or barium-containing contrast media has been administered, a specimen should not be collected for at least 96 hours.

  • Allow the specimen to clot for 30 minutes after collection; then centrifuge the specimen to separate serum from the cellular fraction. Serum must be removed from cellular fraction within 4 hours of specimen collection. Avoid hemolysis.

  • Remove the stopper. Carefully pour specimen into a metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer

  • See Trace Metals Analysis Specimen Collection and Transport for complete instructions

Stability

  • Refrigerated (preferred): 28 days

  • Ambient: 28 days

  • Frozen: 28 days

Unacceptable Specimen Conditions

  • Gross hemolysis

  • Gross icterus

Limitations

  • Hemolyzed specimens will cause false elevation of serum zinc levels

  • It is essential that the specimen is collected following the trace metals collection procedure (see Trace Metals Analysis Specimen Collection and Transport)

Methodology

Dynamic Reaction Cell-Inductively Coupled Plasma-Mass Spectrometry (DRC-ICP-MS)

Estimated TAT

1-3 days

Testing Schedule

Monday-Saturday

Retention

14 days

CPT Code(s)

84630

Additional Information
Minimum Sample Volume

0.2 mL

Reference Range
Age (years) Range (mcg/mL)
0 - 10 0.60 - 1.20
≥ 11 0.66 - 1.10
Performing Lab

Mayo

LOINC Code(s)

5763-8