Test Directory
Thyrotropin Receptor Antibody, Serum
Print this pageUpdated Test Information:
Test Description |
Thyrotropin Receptor Antibody, Serum
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Synonym(s) |
Thyrotropin Receptor Ab
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Test ID |
THYRO
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General Information |
Useful for:
Recommended first-line test for detection of thyrotropin receptor (TSHR) antibodies, and used in the following situations: -Differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous clinical findings and/or contraindicated (eg, pregnant or breast-feeding) or nondiagnostic thyroid radioisotope scans -Diagnosis of clinically suspected Graves disease (eg, extrathyroidal manifestation of Graves disease include endocrine exophthalmos, pretibial myxedema, thyroid acropachy) in patients with normal thyroid function tests -Determining the risk of neonatal thyrotoxicosis in a fetus of a pregnant female with active or past active Graves disease -Differential diagnosis of gestational thyrotoxicosis versus first trimester manifestation or recurrence of Graves disease -Assessing the risk of Graves disease relapse after antithyroid drug treatment |
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Specimen Type |
Serum
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Specimen Requirements |
Red Top
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Stability |
Refrigerated (preferred) 7 days
Frozen 30 days |
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Unacceptable Specimen Conditions |
Gross hemolysis Reject
Gross lipemia OK |
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Methodology |
Electrochemiluminescence Immunoassay
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Estimated TAT |
1-3 days
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Testing Schedule |
Monday-Saturday
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CPT Code(s) |
83520
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Minimum Sample Volume |
0.5 mL
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Reference Range |
< or =1.75 IU/L
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Performing Lab |
Mayo
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LOINC Code(s) |
5385-0
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