Test Directory

Thyrotropin Receptor Antibody, Serum

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Updated Test Information:

Test Description
Thyrotropin Receptor Antibody, Serum
Synonym(s)
Thyrotropin Receptor Ab
Test ID
THYRO
General Information
Useful for:
Recommended first-line test for detection of thyrotropin receptor (TSHR) antibodies, and used in the following
situations:
-Differential diagnosis of etiology of thyrotoxicosis in patients with ambiguous clinical findings and/or contraindicated
(eg, pregnant or breast-feeding) or nondiagnostic thyroid radioisotope scans
-Diagnosis of clinically suspected Graves disease (eg, extrathyroidal manifestation of Graves disease include
endocrine exophthalmos, pretibial myxedema, thyroid acropachy) in patients with normal thyroid function tests
-Determining the risk of neonatal thyrotoxicosis in a fetus of a pregnant female with active or past active Graves
disease
-Differential diagnosis of gestational thyrotoxicosis versus first trimester manifestation or recurrence of Graves
disease
-Assessing the risk of Graves disease relapse after antithyroid drug treatment
Specimen Type
Serum
Specimen Requirements
Red Top
Stability
Refrigerated (preferred) 7 days
Frozen 30 days
Unacceptable Specimen Conditions
Gross hemolysis Reject
Gross lipemia OK
Methodology
Electrochemiluminescence Immunoassay
Estimated TAT
1-3 days
Testing Schedule
Monday-Saturday
CPT Code(s)
83520
Minimum Sample Volume
0.5 mL
Reference Range
< or =1.75 IU/L
Performing Lab
Mayo
LOINC Code(s)
5385-0