Test Directory

Testosterone, Total by Mass Spectrometry, Serum

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Updated Test Information:

Test Description
Testosterone, Total by Mass Spectrometry, Serum
Synonym(s)
Testosterone, Total
Test ID
TTST
General Information
Useful for:
Evaluation of men with symptoms or signs of possible hypogonadism, such as loss of libido, erectile dysfunction, gynecomastia, osteoporosis, or infertility
Evaluation of boys with delayed or precocious puberty
Monitoring testosterone replacement therapy
Monitoring antiandrogen therapy (eg, used in prostate cancer, precocious puberty, treatment of idiopathic hirsutism, male-to-female transgender disorders, etc.)
Evaluation of women with hirsutism, virilization, and oligoamenorrhea
Evaluation of women with symptoms or signs of possible testosterone deficiency
Evaluation of infants with ambiguous genitalia or virilization
Diagnosis of androgen-secreting tumors
Specimen Type
Serum
Specimen Requirements
Red Top
Stability
Refrigerated (preferred) 14 days
Frozen 60 days
Unacceptable Specimen Conditions
Gross hemolysis OK
Gross lipemia OK
Gross icterus OK
Other Serum Gel
Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Estimated TAT
2-3 days
Testing Schedule
Monday-Saturday
CPT Code(s)
84403
Minimum Sample Volume
0.215 mL
Reference Range

MALES

0-5 months 75-400 ng/dL
6 months-9 years <7-20 ng/dL
10-11 years <7-130 ng/dL
12-13 years <7-800 ng/dL
14 years <7-1,200 ng/dL
15-16 years 100-1,200 ng/dL
17-18 years 300-1,200 ng/dL
> or =19 years 240-950 ng/dL
Tanner Stages*
I (prepubertal) <7-20
II 8-66
III 26-800
IV 85-1,200
V (young adult) 300-950

FEMALE

0-5 months 20-80 ng/dL
6 months-9 years <7-20 ng/dL
10-11 years <7-44 ng/dL
12-16 years <7-75 ng/dL
17-18 years 20-75 ng/dL
> or =19 years 8-60 ng/dL
Tanner Stages*
I (prepubertal) <7-20
II <7-47
III 17-75
IV 20-75
V (young adult) 12-60

*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (+/-2) years and for girls at a median age of 10.5 (+/-2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. For boys, there is no definite proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (young adult) should be reached by age 18.

Performing Lab
Mayo
LOINC Code(s)
2986-8