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Pregnenolone, Serum

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Updated Test Information:

Test Description
Pregnenolone, Serum
Test ID
PREGN
General Information

Useful for:



  • An ancillary test for congenital adrenal hyperplasia, particularly in situations in which a diagnosis of 21-hydroxylase and 11-hydroxylase deficiency have been ruled out

  • Confirming a diagnosis of 3-beta-hydroxy dehydrogenase deficiency

  • See Steroid Pathways
Specimen Type

Serum
Specimen Requirements

  • Preferred: Red Top

  • Acceptable: Serum Gel (SST)
Minimum Sample Volume

0.5 mL
Stability

Frozen: 28 days
Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Estimated TAT

2-6 days
Testing Schedule

Monday, Tuesday, Thursday
CPT Code(s)

84140
Reference Range
Age (years) Males (ng/dL) Females (ng/dL)
0 - 6 Not Established
7 - 9 < 206 < 151
10 - 12 < 152 19 - 220
13 - 15 18 - 197 22 - 210
16 - 17 17 - 228 22 - 229
≥ 18 33 - 248
Tanner Stages
Stage I < 157 < 172
Stage II < 144 22 - 229
Stage III < 215 34 - 215
Stage IV - V 19 - 201 26 - 235

 

 

 
Performing Lab

Mayo
LOINC Code(s)

2837-3
Additional Information