Laboratory Services
dsDNA Antibody
Print this pageUpdated Test Information:
| Test Description |
dsDNA Antibody
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| Synonym(s) |
Double stranded DNA, ANA, Antinuclear Antibodies, Anti-DNA
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| Test ID |
DSDNA
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| General Information |
dsDNA antibodies are a disease specific serological marker for the diagnosis and disease management of patients with systemic lupus erythematosus (SLE). More than 90% of sera from patients with active SLE contain dsDNA antibodies. Smaller amounts may be present in patients with other rheumatic disorders, chronic active hepatitis, infectious mononucleosis, and biliary cirrhosis. Assay results should be used in conjunction with clinical findings and other serological tests.
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| Specimen Type |
Serum
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| Alternate Specimen Type |
Plasma (Li-Heparin, EDTA, or Citrate)
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| Specimen Requirements |
Tiger
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| Minimum Sample Volume |
1 mL
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| Pediatric Min. Volume (if applicable) |
500 uL
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| Additional Processing Details |
Caution: Serum/plasma samples are not to be repeatedly frozen and thawed, since this can cause analyte deterioration. They are to be thawed only once.
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| Stability |
Stored at 22˚C: 8 hrs
Stored at 2-8˚C: 48 hrs If assays are not completed within 48 hrs or the specimen is to be stored beyond 48 hrs, the serum/plasma should be frozen at or below -20˚C. |
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| Unacceptable Specimen Conditions |
Lipemic, hemolyzed or microbially contaminated samples.
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| Methodology |
Fluorescent enzyme immunoassay (FEIA)
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| Estimated TAT |
2-5 days
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| Testing Schedule |
Monday-Saturday, alternating days
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| CPT Code(s) |
86225
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| Reference Range |
Negative < 10 IU/mL
Equivocal 10-15 IU/mL Positive > 15 IU/mL |
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| Performing Lab |
Incyte Diagnostics
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| LOINC Code(s) |
33799-8
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