Laboratory Services

Cytomegalovirus (CMV) Antibodies, IgM, Serum

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Updated Test Information:

Test Description
Cytomegalovirus (CMV) Antibodies, IgM, Serum
Synonym(s)

Cytomegalovirus; Cytomegalovirus, IgM (Immunoglobulin M); Torch IgM

Test ID
CMVM
General Information

Useful for:



  • Diagnosis of acute infection with cytomegalovirus (CMV)

  • This test should not be used for screening blood or plasma donors

Specimen Type

Serum

Specimen Requirements

  • Preferred: Serum Gel

  • Acceptable: Red Top

Minimum Sample Volume

0.4 mL

Stability

  • Refrigerated (preferred): 14 days

  • Frozen: 14 days

Unacceptable Specimen Conditions

  • Gross hemolysis

  • Gross lipemia

  • Gross icterus

  • Heat-inactivated specimen

Limitations

  • Sera drawn very early during the acute stage of infection may have undetectable levels of cytomegalovirus (CMV) IgM

  • Immunocompromised patients may have impaired immune responses and nonreactive IgM results may be due to delayed seroconversion and do not rule-out current infection

  • CMV IgM results should not be used alone to diagnose CMV infection. Results should be considered in conjunction with clinical presentation, patient history, and other laboratory findings. In cases of suspected disease, submit a second sample for testing in 10 to 14 days

  • The performance characteristics of these assays have not been evaluated in immunosuppressed or organ transplant recipients and have not been established for cord blood or for testing of neonates

  • Immune complexes or other immunoglobulin aggregates present in patient samples may cause increased nonspecific binding and produce false-positive results

  • Potential cross-reactivity for CMV IgM may occur with specimens positive for Epstein-Barr virus viral capsid antigen IgM and parvovirus B19 IgM.

Methodology

Multiplex Flow Immunoassay (MFI)

Estimated TAT

1-3 days

Testing Schedule

Monday-Saturday

Retention

14 days

CPT Code(s)

86645

Reference Range

Negative

Performing Lab

Mayo

LOINC Code(s)

24119-0

Additional Information