Laboratory Services

Clozapine, Serum

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Updated Test Information:

Test Description
Clozapine, Serum
Synonym(s)

Clozapine (Clozaril); Clozaril (Clozapine)

Test ID
CLZ
General Information

Monitoring patient compliance. An aid to achieving desired serum levels.

Container Type

Red Top

Specimen Type

Serum

Specimen Requirements

1 mL

Specimen Collection / Processing Instructions

Centrifuge and aliquot serum into plastic vial within 2 hours of collection.

Minimum Sample Volume

0.6 mL

Stability

Refrigerated (preferred) 28 days
Frozen 28 days
Ambient 7 days

Unacceptable Specimen Conditions

Gross icterus, SST

Methodology

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Estimated TAT

3 to 5 days

Testing Schedule

Monday through Friday

Test Includes

Clozapine, Norclozapine, Clozapine + Norclozapine

Retention

2 weeks

CPT Code(s)

80159

Reference Range

CLOZAPINE


Therapeutic range: 350-600 ng/m


NORCLOZAPINE


Therapeutic range: Not well established


CLOZAPINE + NORCLOZAPINE


Therapeutic range: Not well established"

STAT Orderable (Y/N)

No

Performing Lab

Mayo

LOINC Code(s)

65632-2