BCR/ABL/ASS1 t(9;22), CMLPrint this page
Updated Test Information:
BCR/ABL/ASS1 t(9;22), CML
CML, ALL, MPN, Philadelphia chromosome, Philadelphia translocation
Probes: BCR (22q11.23)/ABL (9q34.12)/ASS1(9q34.11)
Disease(s): Chronic Myelogenous Leukemia (CML), Acute Lymphoblastic Leukemia (ALL), Myeloproliferative neoplasms (MPN)
Bone Marrow Aspirate and Peripheral Blood
|Additional Processing Details||
Transport to the testing lab at room temp is acceptable. Do not allow sample to overheat or freeze. Use cold pack for transport, making sure cold pack is not in direct contact with specimen
Complete the Incyte Diagnostics hematology requisition with the patient's demographics and relevant clinical history. Label the specimen containers with patient's full name, second unique identifier, and specimen site/source. Please provide a copy of the patient's complete blood count (CBC) report.
|Unacceptable Specimen Conditions||
Specimen containers without two (2) patient identifiers, specimens submitted in inappropriate collection media, frozen specimens.
Fluorescence in-Situ Hybridization (FISH)
3-5 working days from receipt, can be ordered as a STAT result 24-48 hrs. from receipt.
7 days after release of final report
Clinical Significance: Translocation 9;22 is seen in chronic myelogenous leukemia and acute lymphoblastic leukemia
If Flow Cytometry studies are also being ordered, it is preferable to submit an EDTA (purple top) tube specifically for Flow Cytometry. If only one tube can be submitted, please submit one sodium heparin (green top) tube for both FISH and Flow Cytometry studies.