ALK for NSCLC (Anaplastic lymphoma kinase)Print this page
Updated Test Information:
ALK for NSCLC (Anaplastic lymphoma kinase)
Probes: ALK (2p23)
Disease(s): ALK, Non-small cell lung carcinoma (NSCLC)
Formalin fixed paraffin embedded (FFPE) tissue blocks or
|Additional Processing Details||
Transport to the testing lab at room temp is acceptable. Do not allow sample to overheat. Use cold pack for transport, making sure cold pack is not in direct contact with specimen
Complete the Incyte Diagnostics hematology requisition with the patient's demographics and relevant clinical history. Label the specimen containers with patient's full name, second unique identifier, and specimen site/source.
|Unacceptable Specimen Conditions||
Specimen containers without two (2) patient identifiers, specimens submitted on non-positively charged slides, paraffin blocks that have been overheated or frozen, specimens without a H&E slide, slides or paraffin blocks with no tissue remaining, Samples fixed in fixative other than 10% neutral buffered formalin.
Fluorescence in-Situ Hybridization (FISH)
4-7 working days from receipt
Clinical Significance: ALK gene rearrangements are found in 3-5% of non-small cell lung carcinoma (NSCLC).