Laboratory Services

Beta-2 Glycoprotein 1 Antibody, IgG

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Updated Test Information:

Test Description
Beta-2 Glycoprotein 1 Antibody, IgG
Synonym(s)

Antiphospholipid Syndrome, APS

Test ID
BETA2G
General Information

Beta-2 Glycoprotein 1, apolipoprotein H, is a cofactor in antiphospholipid antibody binding and is a critical antigen in the antiphospholipid syndrome (APS). These antibodies are important diagnostic markers for antiphospholipid syndrome (APS) due to their increased specificity and lower cross-reactivity. Assay results should be used in conjunction with clinical findings and other serological tests.

Specimen Type

Serum

Alternate Specimen Type

Plasma (Li-Heparin, EDTA, or Citrate)

Specimen Requirements

Tiger

Additional Processing Details

Caution: Serum/plasma samples are not to be repeatedly frozen and thawed, since this can cause analyte deterioration. They are to be thawed only once.

Stability

Stored at 22˚C: 8 hrs
Stored at 2-8˚C: 1 week
If assays are not completed within 1 week or the specimen is to be stored beyond 1 week, the serum/plasma should be frozen at or below -20˚C.

Unacceptable Specimen Conditions

Lipemic, hemolyzed or microbially contaminated samples.

Methodology

Fluorescent enzyme immunoassay (FEIA)

Estimated TAT

2-5 days

Testing Schedule

Monday-Saturday, alternating days

CPT Code(s)

86146

Minimum Sample Volume

1 mL

Pediatric Min. Volume (if applicable)

500 uL

Reference Range

Negative < 7 U/mL
Equivocal 7-10 U/mL
Positive > 10 U/mL

Performing Lab

Incyte Diagnostics

LOINC Code(s)

44448-9