Antimitochondrial (M2) AntibodyPrint this page
Updated Test Information:
Antimitochondrial (M2) Antibody
AMA, Mitochondrial Antibody
Antimitochondrial antibodies are important diagnostic indicators for patients with Primary Biliary Cirrhosis (PBC), chronic active hepatitis, cryptogenic cirrhosis, as well as in those with clinical but no biochemical evidence of liver disease. The mitochondrial M2 antigen has a 95% specificity for PBC. Assay results should be used in conjunction with clinical findings and other serological tests.
|Alternate Specimen Type||
Plasma (Li-Heparin or EDTA)
|Additional Processing Details||
Caution: Serum/plasma samples are not to be repeatedly frozen and thawed, since this can cause analyte deterioration. They are to be thawed only once.
Stored at 22˚C: 8 hrs
Stored at 2-8˚C: 48 hrs
If assays are not completed within 48 hrs or the specimen is to be stored beyond 48 hrs, the serum/plasma should be frozen at or below -20˚C.
|Unacceptable Specimen Conditions||
Lipemic, hemolyzed or microbially contaminated samples.
Fluorescent enzyme immunoassay (FEIA)
Monday-Saturday, alternating days
|Minimum Sample Volume||
|Pediatric Min. Volume (if applicable)||