Laboratory Services

Antibody Screen

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Updated Test Information:

Test Description
Antibody Screen
Synonym(s)

Indirect Coombs

Test ID
ABS
General Information

Detection of antibodies directed against red blood cell antigens. An Antibody Screen of expectant mothers may indicate potential for hemolytic disease of the fetus/newborn.

Specimen Type

Whole Blood

Alternate Specimen Type

None

Specimen Requirements

2 Lavender or 1 Pink (EDTA)

Specimen Collection / Processing Instructions

Lavender - The specimen should be tested as soon as possible after collection. If testing is delayed, EDTA specimens should be stored at 2 to 8°C. Draw an extra lavender tube in case of Antibody ID reflex

Minimum Sample Volume

6 ml

Pediatric Min. Volume (if applicable)

6 ml

Stability

Refrigerated 10 days

Unacceptable Specimen Conditions

Grossly hemolyzed, icteric, or lipemic samples. Frozen samples. Bacterial contamination.

Limitations

Abnormal plasma proteins, cold autoagglutinins, positive direct antiglobulin test, and, in some cases, bacteremia may interfere with test interpretation.

Methodology

Hemagglutination/gel filtration

Estimated TAT

1-3 days

Testing Schedule

Monday-Saturday

CPT Code(s)

86850

Reference Range

Negative

Reflex Conditions

If antibody screen is positive, antibody identification and titer will be performed. Please allow additional time for testing to be completed.

Performing Lab

Incyte Diagnostics

LOINC Code(s)

890-4